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A2521

NEDD9 Rabbit polyclonal antibody

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£152.00

SKU:
A2521
Additional Names:
CAS-L|CAS2|CASL|CASS2|HEF1|NEDD9
Application:
ELISA, WB, IHC-P, IF, ICC
Molecular Weight:
105kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
SSLSASPAQDKRLFLDPDTAIERLQRLQQALEMGVSSLMALVTTDWRCYGYMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELILHNKMKRELQRVEDSHQILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPDDAKQLTTTINTNAEALFRPG
Uniprot:
Q14511
Synonyms:
Cas scaffolding protein family member 2;CAS-L;cas-like docking;CAS2;CASL;CASS2;Crk-associated substrate related protein Cas-L;CRK-associated substrate-related protein;enhancer of filamentation 1;Enhancer of filamentation 1 p55;HEF1;neural precursor cell expressed developmentally down-regulated protein 9;p105;p130Cas-related protein;renal carcinoma antigen NY-REN-12
Extra Details:
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants.
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Blue Ice