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A24836

PP2A-AB Beta/PR65B Beta/PPP2R1B Rabbit polyclonal antibody

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£152.00

SKU:
A24836
Additional Names:
PP2A-Abeta|PP2A-AB Beta/PR65B Beta/PPP2R1B|PPP2R1B|PR65B|protein phosphatase 2 scaffold subunit Abeta
Application:
ELISA, WB
Molecular Weight:
66kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Rat
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
ANDPNYLHRMTTLFCINALSEACGQEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQKLGQDEDMDVKYFAQEAISVLALA
Uniprot:
P30154
Synonyms:
PP2A subunit A isoform PR65-beta;PP2A subunit A isoform R1-beta;PP2A-Abeta;PR65B;protein phosphatase 2, regulatory subunit A, beta;protein phosphatase 2, structural/regulatory subunit A, beta;serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
Extra Details:
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
Shipping Conditions:
Blue Ice