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A2481

FLNB Rabbit polyclonal antibody

Size

£152.00

SKU:
A2481
Additional Names:
ABP-278|ABP-280|AOI|FH1|FLN-B|FLN1L|FLNB|LRS1|SCT|TABP|TAP
Application:
ELISA, WB, IHC-P, IF, ICC
Molecular Weight:
298kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
PDGTEAEADVIENEDGTYDIFYTAAKPGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVNACPPGFRPWVTEEAYVPVSDMNGLGFKPFDLVIPFA
Uniprot:
O75369
Synonyms:
ABP-278;ABP-280;ABP-280 homolog;actin binding protein 278;actin-binding-like protein;AOI;beta-filamin;FH1;filamin B, beta;filamin homolog 1;filamin-3;filamin-B;FLN-B;FLN1L;Larsen syndrome 1 (autosomal dominant);LRS1;SCT;TABP;TAP;thyroid autoantigen;Truncated actin-binding protein
Extra Details:
This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
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Blue Ice