Importin Alpha 5/KPNA1 Rabbit monoclonal antibody

Size

POA

SKU:: A24117
Additional Names:: Importin Alpha 5/KPNA1|IPOA5|NPI-1|RCH2|SRP1
Application:: ELISA, WB, IHC-P, IF, ICC
Molecular Weight:: 62kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQISNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRR
Uniprot:: P52294
Synonyms:: importin alpha 5;importin subunit alpha-1;importin subunit alpha-5;importin-alpha-S1;IPOA5;karyopherin alpha 1 (importin alpha 5);Karyopherin subunit alpha-1;NPI-1;nucleoprotein interactor 1;RAG cohort protein 2;RCH2;recombination activating gene cohort 2;SRP1;SRP1-beta
Extra Details:: The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.

Shipping Conditions:: Blue Ice