HRP-conjugated Digoxin Rabbit monoclonal antibody

Size

POA

SKU:: A24114
Additional Names:: Digoxin|HRP-conjugated Digoxin
Application:: ELISA, Dot blot
Molecular Weight:: Refer to figures
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Immunogen:: Chemical compounds corresponding to Digoxin.
Formulation:: Unmodified
Sequence:: Digoxin conjugated to KLH
Extra Details:: Digoxin is a cardiac glycoside. Digoxin inhibits the sodium potassium adenosine triphosphatase (ATPase) pump, thereby increasing intracellular calcium and enhancing cardiac contractility. This agent also acts directly on the atrioventricular node to suppress conduction, thereby slowing conduction velocity. Apparently due to its effects on intracellular calcium concentrations, digoxin induces apoptosis of tumor cells via a pathway involving mitochondrial cytochrome c, caspases 8 and 3.