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A23670

GPT2 Rabbit polyclonal antibody

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£152.00

SKU:
A23670
Additional Names:
ALT2|GPT 2|GPT2|MRT49|NEDSPM
Application:
ELISA, WB
Molecular Weight:
58 kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
DCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVL
Uniprot:
Q8TD30
Synonyms:
alanine aminotransferase 2;ALT2;glutamate pyruvate transaminase 2;glutamic pyruvate transaminase (alanine aminotransferase) 2;glutamic pyruvate transaminase 2;glutamic--alanine transaminase 2;Glutamic--pyruvic transaminase 2;GPT 2;MRT49;NEDSPM
Extra Details:
This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice