SMARCA2 / BRM Rabbit monoclonal antibody

Size

POA

SKU:: A23291
Additional Names:: BAF190|BIS|BRM|hBRM|hSNF2a|NCBRS|SMARCA2 / BRM|SNF2|SNF2L2|SNF2LA|Sth1p|SWI2
Application:: ChIP, ELISA, WB, IHC-P, IF, ICC, IP
Molecular Weight:: 200 kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: A synthetic peptide corresponding to a sequence within amino acids 201-300 of human SMARCA2 (NP_003061.3).
Formulation:: Unmodified
Sequence:: TLQLAVQGKRTLPGLQQQQQQQQQQQQQQQQQQQQQQQPQQQPPQPQTQQQQQPALVNYNRPSGPGPELSGPSTPQKLPVPAPGGRPSPAPPAAAQPPAA
Uniprot:: P51531
Synonyms:: ATP-dependent helicase SMARCA2;BAF190;BAF190B;BIS;brahma homolog;BRG1-associated factor 190B;BRM;global transcription activator homologous sequence;hBRM;hSNF2a;NCBRS;probable global transcription activator SNF2L2;protein brahma homolog;SNF2;SNF2-alpha;SNF2/SWI2-like protein 2;SNF2L2;SNF2LA;Sth1p;sucrose nonfermenting 2-like protein 2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2;SWI2
Extra Details:: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.

Shipping Conditions:: Blue Ice