IL17A Rabbit monoclonal antibody

Size

POA

SKU:: A23226
Additional Names:: Ctla-8|Ctla8|IL-17|IL-17A|Il17|IL17A
Application:: ELISA, WB
Molecular Weight:: 17kDa (Recombinant Protein)
Species Reactivity:: Mouse
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: AAIIPQSSACPNTEAKDFLQNVKVNLKVFNSLGAKVSSRRPSDYLNRSTSPWTLHRNEDPDRYPSVIWEAQCRHQRCVNAEGKLDHHMNSVLIQQEILVLKREPESCPFTFRVEKMLVGVGCTCVASIVRQAA
Uniprot:: Q62386
Synonyms:: Ctl;Ctla;Ctla-8;Ctla8;cytotoxic T-lymphocyte-associated antigen 8;Il;IL-;IL-17;IL-17A;Il17;interleukin-17A
Extra Details:: This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. The encoded protein plays a central role in host defense against diverse pathogens. The encoded protein is produced by activated T-cells and certain cell types of innate immune system. The active protein functions as either a homodimer with other interleukin-17 family members and signals through the interleukin-17 receptor to induce inflammatory cytokine production. Aberrant expression of this gene is associated with autoinflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.