HTR3A Rabbit monoclonal antibody

Size

POA

SKU:: A22906
Additional Names:: 5-HT-3|5-HT3A|5-HT3R|5HT3R|HTR3|HTR3A
Application:: ELISA, WB, IHC-P, IF, ICC
Molecular Weight:: 55kDa
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: P46098
Synonyms:: 5-HT-3;5-HT3A;5-HT3R;5-hydroxytryptamine (serotonin) receptor 3A, ionotropic;5-hydroxytryptamine receptor 3;5-hydroxytryptamine receptor 3A;5HT3 serotonin receptor;5HT3R;HTR3;serotonin receptor 3A;serotonin-gated ion channel receptor
Extra Details:: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.