A22248
NKX2-1 Rabbit monoclonal antibody
Size
POA
- SKU:
- A22248
- Additional Names:
- BCH|BHC|NK-2|NKX2.1|NKX2A|NMTC1|T/EBP|TEBP|TITF1|TTF-1|TTF1
- Application:
- ELISA, IHC-P
- Molecular Weight:
- Refer to figures
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- MSMSPKHTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQGQAAPPTAAMQQHAVGHHGAVTAAYHMTAAGVPQLSHSAVGGYCNGNLGNMSELPPY
- Uniprot:
- P43699
- Synonyms:
- BCH;BHC;homeobox protein NK-2 homolog A;homeobox protein Nkx-2.1;NK-2;NK-2 homolog A;NKX2.1;NKX2A;NMTC1;T/EBP;TEBP;thyroid nuclear factor 1;thyroid transcription factor 1;thyroid-specific enhancer-binding protein;TITF1;TTF-1;TTF1
- Extra Details:
- This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.
- Shipping Conditions:
- Blue Ice