StAR Rabbit monoclonal antibody

Size

POA

SKU:: A22166
Additional Names:: StAR|STARD1
Application:: ELISA, WB, IHC-P, IF
Molecular Weight:: 28kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: SQQDNGDKVMSKVVPDVGKVFRLEVVVDQPMERLYEELVERMEAMGEWNPNVKEIKVLQKIGKDTFITHELAAEAAGNLVGPRDFVSVRCAKRRGSTCVLA
Uniprot:: P49675
Synonyms:: cholesterol trafficker;mitochondrial steroid acute regulatory protein;StAR related lipid transfer (START) domain containing 1;STARD1;START domain containing 1;START domain-containing protein 1;steroid acute regulatory protein;steroidogenic acute regulator;steroidogenic acute regulatory protein, mitochondrial;testis secretory sperm-binding protein Li 241mP
Extra Details:: The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.