A22137
ALKBH5 Rabbit monoclonal antibody
Size
POA
- SKU:
- A22137
- Additional Names:
- ABH5|ALKBH5|OFOXD|OFOXD1
- Application:
- ELISA, WB
- Molecular Weight:
- 45-48kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- PERSDYEEQQLQKEEEARKVKSGIRQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTYGAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLETKSLSSSVLPPSYASDRLSGNNRDPALKPKRSHRKADPDAAHRPRILEMDKEENRRSVLLPTHRRRGSFSSENYWRKSYESSEDCSEAAGSPARKVKMRRH
- Uniprot:
- Q6P6C2
- Synonyms:
- ABH5;AlkB family member 5, RNA demethylase;alkB, alkylation repair homolog 5;alkylated DNA repair protein alkB homolog 5;alpha-ketoglutarate-dependent dioxygenase alkB homolog 5;OFOXD;OFOXD1;oxoglutarate and iron-dependent oxygenase domain containing;probable alpha-ketoglutarate-dependent dioxygenase ABH5;RNA demethylase ALKBH5
- Extra Details:
- Enables mRNA N6-methyladenosine dioxygenase activity. Involved in RNA metabolic process; mRNA export from nucleus; and response to hypoxia. Located in Golgi apparatus; cytosol; and nuclear speck.ALKBH5, also named as ABH5 and OFOXD1, is a Dioxygenase that demethylates RNA by oxidative demethylation. It is a mammalian demethylase that oxidatively reverses m6A in mRNA in vitro and in vivo. ALKBH5 is required for spermatogenesis.
- Shipping Conditions:
- Blue Ice