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  2. Monoclonal

A21237

CLCN1 Rabbit monoclonal antibody

Size

POA

SKU:
A21237
Additional Names:
CLC1|CLCN1
Application:
ELISA, WB
Molecular Weight:
109 kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
NTTSTRKSTGAPPSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESPGLEEELADILQGPSLRSTDEEDEDELIL
Uniprot:
P35523
Synonyms:
chloride channel 1, skeletal muscle;chloride channel protein 1;chloride channel protein, skeletal muscle;chloride channel, voltage-sensitive 1;clC-1;CLC1
Extra Details:
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice