Transglutaminase 2 (TGM2) Rabbit monoclonal antibody

Size

POA

SKU:: A21184
Additional Names:: G(h)|hTG2|TG(C)|TGC|Transglutaminase 2 (TGM2)|tTG
Application:: ELISA, WB, IHC-P, IF, ICC
Molecular Weight:: 77kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: DITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVGQSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVIIGPA
Uniprot:: P21980
Synonyms:: C polypeptide, protein-glutamine-gamma-glutamyltransferase;erythrocyte transglutaminase;G(h);heart G alpha(h);hhG alpha(h);hTG2;isopeptidase TGM2;protein G alpha(h);protein-glutamine deamidase TGM2;protein-glutamine dopaminyltransferase TGM2;protein-glutamine gamma-glutamyltransferase 2;protein-glutamine histaminyltransferase TGM2;protein-glutamine noradrenalinyltransferase TGM2;protein-glutamine serotonyltransferase TGM2;TG(C);TGase C;TGase H;TGase II;TGase-2;TGC;tissue transglutaminase;transglutaminase C;transglutaminase H;transglutaminase II;Transglutaminase-2;tTG;tTgase
Extra Details:: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.

Shipping Conditions:: Blue Ice