Ube2L3 / UBCH7 Rabbit monoclonal antibody

Size

POA

SKU:: A20887
Additional Names:: E2-F1|L-UBC|UBCH7|UbcM4|Ube2L3 / UBCH7
Application:: ELISA, WB, IHC-P, IF, ICC
Molecular Weight:: 18kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: INFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
Uniprot:: P68036
Synonyms:: E2 ubiquitin-conjugating enzyme L3;E2-F1;L-UBC;UBCH7;UbcM4;ubiquitin carrier protein L3;ubiquitin conjugating enzyme E2L 3;ubiquitin-conjugating enzyme E2 L3;ubiquitin-conjugating enzyme E2-F1;ubiquitin-conjugating enzyme UBCH7;ubiquitin-protein ligase L3
Extra Details:: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene.