FGR Rabbit polyclonal antibody

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£152.00

SKU:: A2075
Additional Names:: c-fgr|c-src2|FGR|p55-Fgr|p55c-fgr|p58-Fgr|p58c-fgr|SRC2
Application:: ELISA, WB, IHC-P
Molecular Weight:: 53kda
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MGCVFCKKLEPVATAKEDAGLEGDFRSYGAADHYGPDPTKARPASSFAHIPNYSNFSSQAINPGFLDSGTIRGVSGIGVTLFIALYDYEARTEDDLTFTK
Uniprot:: P09769
Synonyms:: c-fgr;c-fgr protooncogene;c-src-2 proto-oncogene;c-src2;feline Gardner-Rasheed sarcoma viral oncogene homolog;Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog;p55-c-fgr protein;p55-Fgr;p55c-fgr;p58-Fgr;p58c-fgr;proto-oncogene c-Fgr;proto-oncogene tyrosine-protein kinase FGR;SRC2;tyrosine-protein kinase Fgr;v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog
Extra Details:: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Shipping Conditions:: Blue Ice