A1975
PSMB5 Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A1975
- Additional Names:
- LMPX|MB1|PSMB5
- Application:
- ELISA, WB, IHC-P, IF, ICC, IP
- Molecular Weight:
- 22kDa/28kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP
- Uniprot:
- P28074
- Synonyms:
- LMPX;macropain epsilon chain;MB1;multicatalytic endopeptidase complex epsilon chain;proteasome (prosome, macropain) subunit, beta type, 5;proteasome beta 5 subunit;proteasome catalytic subunit 3;proteasome chain 6;proteasome epsilon chain;proteasome subunit beta 5;proteasome subunit beta type-5;proteasome subunit MB1;proteasome subunit X;proteasome subunit, beta type, 5;PSX large multifunctional protease X;testicular tissue protein Li 153;X
- Extra Details:
- The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice