[KO Validated] ATG5 Rabbit monoclonal antibody

Size

POA

SKU:: A19677
Additional Names:: APG5|APG5-LIKE|APG5L|ASP|G5|hAPG5|SCAR25
Application:: ELISA, WB, IHC-P, IF, IP
Molecular Weight:: 55kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVSYLTLVTDKVKKHFQKVMRQEDISEIWFEYEGTPLKWHYPIGLLFDLLASSSALPWNI
Uniprot:: Q9H1Y0
Synonyms:: APG5;APG5 autophagy 5-like;APG5-LIKE;APG5L;apoptosis-specific protein;ASP;ATG5 autophagy related 5 homolog;autophagy protein 5;hAPG5;SCAR25
Extra Details:: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.