A19540
TSC2 Rabbit monoclonal antibody
Size
POA
- SKU:
- A19540
- Additional Names:
- LAM|PPP1R160|TSC2|TSC4
- Application:
- ELISA, WB, IP
- Molecular Weight:
- 200kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- AKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV
- Uniprot:
- P49815
- Synonyms:
- LAM;PPP1R160;protein phosphatase 1, regulatory subunit 160;TSC4;tuberin;tuberous sclerosis 2 protein
- Extra Details:
- This gene is a tumor suppressor gene that encodes the growth inhibitory protein tuberin. Tuberin interacts with hamartin to form the TSC protein complex which functions in the control of cell growth. This TSC protein complex negatively regulates mammalian target of rapamycin complex 1 (mTORC1) signaling which is a major regulator of anabolic cell growth. Mutations in this gene have been associated with tuberous sclerosis and lymphangioleiomyomatosis.
- Shipping Conditions:
- Blue Ice