FTO Rabbit polyclonal antibody

Size

£152.00

SKU:: A18672
Application:: ELISA, WB
Molecular Weight:: 60kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MKPRQRKQYFRNMKRSDDSEREKRRKRRRLLQELGEQRIPYLSPTDPGFQDLWDSSYAGLALRQSGTLPEGLHEKVQSALLTLQRHGCLLRDLVRVRDRDVFTAVSRALVGQPGYTYRYLDTRLFTIPWHCEGEEGQKDEKGKPCCDSDLRDACKALWELNQFFCSDVKQQTNARGVKRTRSDTENSEDAPGEGMCEEESVKDRLVEEKTIEEEEEDSGQGCSHSSPPSSTPPAAQASLVQFNVTLINYMNPAAMTQLKEEPYYGMGKMAVGWHHDENLVPLSPVAVYSYSCPAEPKNEGVTEKDGEGKSKEKEREAKGEGTSTEEVKKEGEASVKEDVEKEKTCWRVG
Synonyms:: AlkB homolog 9;ALKBH9;alpha-ketoglutarate-dependent dioxygenase FTO;BMIQ14;fat mass and obesity associated;fat mass and obesity-associated protein;GDFD;m6A(m)-demethylase FTO;mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO;mRNA N(6)-methyladenosine demethylase FTO;protein fto;tRNA N1-methyl adenine demethylase FTO;U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO;U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
Extra Details:: Predicted to enable 2-oxoglutarate-dependent dioxygenase activity and ferrous iron binding activity. Acts upstream of or within several processes, including cilium assembly; left/right pattern formation; and positive regulation of canonical Wnt signaling pathway. Predicted to be located in cytoplasm and nuclear speck. Human ortholog(s) of this gene implicated in obesity. Orthologous to human FTO (FTO alpha-ketoglutarate dependent dioxygenase).

Shipping Conditions:: Blue Ice