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A18495

PNPO Rabbit polyclonal antibody

Size

£152.00

SKU:
A18495
Additional Names:
HEL-S-302|PDXPO|PNPO
Application:
ELISA, WB, IF, ICC
Molecular Weight:
30kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:
MTCWLRGVTATFGRPAEWPGYLSHLCGRSAAMDLGPMRKSYRGDREAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKGFGKDGFRFFTNFESRKGKELDSNPFASLVFYWEPLNRQVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPDREYLRKKNEELEQLYQDQEVPKPKSWGGYVLYPQVMEFWQGQTNRLHDRIVFRRGLPTGDSPLGPMTHRGEEDWLYERLAP
Uniprot:
Q9NVS9
Synonyms:
epididymis secretory protein Li 302;epididymis secretory sperm binding protein;HEL-S-302;PDXPO;pyridoxal 5'-phosphate synthase;pyridoxamine-phosphate oxidase;pyridoxine 5'-phosphate oxidase;pyridoxine-5'-phosphate oxidase
Extra Details:
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.
Shipping Conditions:
Blue Ice