A18325
H2-Aa Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A18325
- Additional Names:
- Aalpha|H-2Aa|H2-Aa|H2Aa|I-Aalpha|Ia-1|Ia1|IAalpha
- Application:
- ELISA, WB
- Molecular Weight:
- 28 kDa
- Species Reactivity:
- Mouse
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Sequence:
- IEADHVGTYGISVYQSPGDIGQYTFEFDGDELFYVDLDKKETVWMLPEFGQLASFDPQGGLQNIAVVKHNLGVLTKRSNSTPATNEAPQATVFPKSPVLLGQPNTLICFVDNIFPPVINITWLRNSKSVADGVYETSFFVNRDYSFHKLSYLTFIPSDDDIYDCKVEHWGLEEPVLKHWEPE
- Uniprot:
- P14434
- Synonyms:
- A;Aalpha;H-2;H-2 class II histocompatibility antigen, A-B alpha chain;H-2 class II histocompatibility antigen, A-F alpha chain;H-2 class II histocompatibility antigen, A-K alpha chain;H-2 class II histocompatibility antigen, A-Q alpha chain;H-2 class II histocompatibility antigen, A-R alpha chain;H-2 class II histocompatibility antigen, A-S alpha chain;H-2 class II histocompatibility antigen, A-U alpha chain;H-2Aa;H2Aa;histocompatibility 2, class II antigen A, alpha;histocompatibility 2, class II antigen A, alpha, promoter 1;I;I-;I-Aalpha;Ia;Ia-1;Ia1;IAalpha;major histocompatibility protein class II alpha chain;MHC class II antigen alpha chain;MHC-II I-A(d) alpha
- Extra Details:
- Enables peptide antigen binding activity. Involved in response to interferon-gamma. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and positive regulation of T cell differentiation. Located in external side of plasma membrane and lysosome. Part of MHC class II protein complex. Is expressed in central nervous system; retina; and thymus primordium. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); gastrointestinal system cancer (multiple); glomerulonephritis (multiple); hematologic cancer (multiple); and systemic scleroderma (multiple). Orthologous to several human genes including HLA-DQA1 (major histocompatibility complex, class II, DQ alpha 1).
- Shipping Conditions:
- Blue Ice