[KO Validated] TMED10 Rabbit polyclonal antibody

Size

POA

SKU:: A18090
Additional Names:: 10|p23|P24(DELTA)|p24d1|S31I125|S31III125|Tmp-21-I|TMP21
Application:: ELISA, WB, IHC-P, IF, ICC
Molecular Weight:: 21kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: HLPINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFS
Uniprot:: P49755
Synonyms:: 21 kDa transmembrane trafficking protein;21 kDa transmembrane-trafficking protein;p23;p24 family protein delta-1;P24(DELTA);p24d1;p24delta;p24delta1;S31I125;S31III125;testicular tissue protein Li 206;Tmp-21-I;TMP21;transmembrane emp24 domain-containing protein 10;transmembrane emp24-like trafficking protein 10;transmembrane protein Tmp21
Extra Details:: This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

Shipping Conditions:: Blue Ice