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A1797

GADD45A Rabbit polyclonal antibody

Size

£152.00

SKU:
A1797
Additional Names:
DDIT1|GADD45|GADD45A
Application:
ELISA, WB, IHC-P
Molecular Weight:
18kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLAADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPPDLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER
Uniprot:
P24522
Synonyms:
DDIT-1;DDIT1;DNA damage-inducible transcript 1 protein;DNA damage-inducible transcript-1;GADD45;growth arrest and DNA damage-inducible protein GADD45 alpha;growth arrest and DNA-damage-inducible 45 alpha
Extra Details:
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Shipping Conditions:
Blue Ice