PDE3A Rabbit polyclonal antibody

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£152.00

SKU:: A17919
Additional Names:: CGI-PDE|CGI-PDE A|CGI-PDE-A|HTNB|PDE3A
Application:: ELISA, WB, IHC-P, IF, ICC
Molecular Weight:: 125 kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: This information is considered to be commercially sensitive.
Sequence:: LLSTQLTFQAIHKPRVNPVTSLSENYTCSDSEESSEKDKLAIPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSTSIKLQEAPSSSPDSWNNPVMMTLTKSRSFTSSYAISAANHVKAKKQSRPGALAKISPLSSPCSSPLQGTPASSLVSKISAVQFPESADTTAKQSLGSHRALTYTQSAPDLSPQILTPPVICSSCGRPYSQGNPADEPLERSGVATRTPSRTDDTAQVTSDYETNNNSDSSDIVQNEDETECLREPLRKASACSTYA
Uniprot:: Q14432
Synonyms:: cAMP phosphodiesterase, myocardial cGMP-inhibited;CGI-PDE;CGI-PDE A;CGI-PDE-A;cGMP-inhibited 3',5'-cyclic phosphodiesterase A;cyclic GMP-inhibited phosphodiesterase A;HTNB;phosphodiesterase 3A, cGMP-inhibited
Extra Details:: This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Shipping Conditions:: Blue Ice