A17737
POGLUT1 Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A17737
- Additional Names:
- C3orf9|CLP46|hCLP46|KDELCL1|KTELC1|LGMD2Z|LGMDR21|MDS010|MDSRP|POGLUT1|Rumi
- Application:
- ELISA, WB, IF, ICC
- Molecular Weight:
- 46kda
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- MYPAWTFWEGGPAVWPIYPTGLGRWDLFREDLVRSAAQWPWKKKNSTAYFRGSRTSPERDPLILLSRKNPKLVDAEYTKNQAWKSMKDTLGKPAAKDVHLVDHCKYKYLFNFRGVAASFRF
- Uniprot:
- Q8NBL1
- Synonyms:
- 9630046K23Rik;C3orf9;CAP10-like 46 kDa protein;CLP46;hCLP46;hRumi;KDELC family like 1;KDELCL1;KTEL (Lys-Tyr-Glu-Leu) containing 1;KTEL motif-containing protein 1;KTELC1;LGMD2Z;LGMDR21;MDS010;MDSRP;myelodysplastic syndromes relative protein;O-glucosyltransferase Rumi homolog;protein O-glucosyltransferase 1;protein O-xylosyltransferase POGLUT1;Rumi;x 010 protein
- Extra Details:
- This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice