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A17608

SF3B4 Rabbit polyclonal antibody

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£152.00

SKU:
A17608
Additional Names:
AFD1|Hsh49|SAP49|SF3B4|SF3b49
Application:
ELISA, WB
Molecular Weight:
44kda
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
MAAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSAAERLLAAQNP
Uniprot:
Q15427
Synonyms:
AFD1;Hsh49;pre-mRNA-splicing factor SF3b 49 kDa subunit;SAP 49;SAP49;SF3b49;SF3b50;spliceosomal protein;spliceosome-associated protein (U2 snRNP);spliceosome-associated protein 49;splicing factor 3B subunit 4;splicing factor 3b, subunit 4, 49kD;splicing factor 3b, subunit 4, 49kDa
Extra Details:
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
Shipping Conditions:
Blue Ice