EXOSC10 Rabbit polyclonal antibody

Size

£152.00

SKU:: A17519
Additional Names:: EXOSC10|p2|p3|p4|PM-Scl|PM/Scl-100|PMSCL|PMSCL2|RRP6|Rrp6p
Application:: ELISA, WB
Molecular Weight:: 110kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
ABP:: No Import Docs
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: VAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR
Uniprot:: Q01780
Synonyms:: autoantigen PM-SCL;Autoantigen PM/Scl 2;exosome component 10;P100 polymyositis-scleroderma overlap syndrome-associated autoantigen;p2;p3;p4;PM-Scl;PM/Scl-100;PMSCL;PMSCL2;polymyositis/scleroderma autoantigen 100 kDa;polymyositis/scleroderma autoantigen 2;RRP6;Rrp6p
Extra Details:: Enables 3'-5'-exoribonuclease activity. Involved in several processes, including RNA catabolic process; maturation of 5.8S rRNA; and negative regulation of telomere maintenance via telomerase. Located in cytosol; nuclear lumen; and transcriptionally active chromatin. Part of nuclear exosome (RNase complex).