NR0B1 Rabbit polyclonal antibody

Size

£152.00

SKU:: A1740
Additional Names:: AHC|AHCH|AHX|DAX-1|DAX1|DSS|GTD|HHG|NR0B1|NROB1|SRXY2
Application:: ELISA, WB, IF, ICC
Molecular Weight:: 48kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNVALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGLPGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSSGALRPVALKSPQVVCEAASA
Uniprot:: P51843
Synonyms:: AHC;AHCH;AHX;DAX-1;DAX1;DSS;DSS-AHC critical region on the X chromosome protein 1;GTD;HHG;NROB1;nuclear hormone receptor;nuclear receptor DAX-1;nuclear receptor subfamily 0 group B member 1;SRXY2;truncated nuclear receptor subfamily 0 group B member 1
Extra Details:: This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.