CFL1 Rabbit polyclonal antibody

Size

£152.00

SKU:: A1704
Additional Names:: CFL|CFL1|cofilin|HEL-S-15
Application:: ELISA, WB
Molecular Weight:: 19kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MASGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATFVKMLPDKDCRYALYDATYETKESKKEDLV
Uniprot:: P23528
Synonyms:: 18 kDa phosphoprotein;CFL;cofilin;cofilin 1 (non-muscle);cofilin-1;Cofilin, non-muscle isoform;epididymis secretory protein Li 15;HEL-S-15;p18
Extra Details:: The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.