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A16906

KCNA1 Rabbit polyclonal antibody

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£152.00

SKU:
A16906
Additional Names:
AEMK|EA1|HBK1|HUK1|KCNA1|KV1.1|MBK1|MK1|RBK1
Application:
ELISA, WB, IF
Molecular Weight:
60kDa/75kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:
QLLHVSSPNLASDSDLSRRSSSTMSKSEYMEIEEDMNNSIAHYRQVNIRTANCTTANQNCVNKSKLLTDV
Uniprot:
Q09470
Synonyms:
AEMK;EA1;HBK1;HUK1;KV1.1;MBK1;MK1;potassium channel, voltage gated shaker related subfamily A, member 1;potassium voltage-gated channel subfamily A member 1;potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia);RBK1;voltage-gated K(+) channel HuKI;voltage-gated potassium channel HBK1;voltage-gated potassium channel subunit Kv1.1
Extra Details:
This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).
Shipping Conditions:
Blue Ice