A16747
SNIP1 Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A16747
- Additional Names:
- NEDHCS|PML1|PMRED|SNIP1
- Application:
- ELISA, WB, IHC-P, IF, ICC
- Molecular Weight:
- 46kda
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Rat
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Sequence:
- SESQELVPRPGGNNKEKEVPAKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCS
- Uniprot:
- Q8TAD8
- Synonyms:
- FHA domain-containing protein SNIP1;PML1;PML1 homolog;PMRED;smad nuclear-interacting protein 1
- Extra Details:
- This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED).
- Shipping Conditions:
- Blue Ice