A16363
CYP11A1 Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A16363
- Additional Names:
- CYP11A|CYP11A1|CYPXIA1|P450SCC
- Application:
- ELISA, WB, IHC-P, IF
- Molecular Weight:
- 50kda
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- ISTRSPRPFNEIPSPGDNGWLNLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVIDPEDVALLFKSEGPNPERFLIPPWVAYHQYYQRPIGVLLKKSAAWKKDRVALNQEVMAPEATKNFLPLLDAVSRDFVSVLHRRIKKAGSGNYSGDISDDLFRFAFESITNVIFGERQGMLEEVVNPEAQRFIDAIYQMFHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSKADIYTQNFYWELRQKGSVHHDYRGILYRLLGDSKMSFEDIKANV
- Uniprot:
- P05108
- Synonyms:
- cholesterol 20-22 desmolase;Cholesterol desmolase;cholesterol monooxygenase (side-chain cleaving);cholesterol side-chain cleavage enzyme, mitochondrial;CYP11A;CYPXIA1;cytochrome P450 11A1;cytochrome P450 family 11 subfamily A polypeptide 1;cytochrome P450, subfamily XIA (cholesterol side chain cleavage);cytochrome P450(scc);P450SCC;steroid 20-22-lyase
- Extra Details:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.
- Shipping Conditions:
- Blue Ice