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A16212

NLRP1 Rabbit polyclonal antibody

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£152.00

SKU:
A16212
Additional Names:
AIADK|CARD7|CIDED|CLR17.1|DEFCAP|DEFCAP-L/S|JRRP|MSPC|NAC|NALP1|NLRP1|PP1044|SLEV1|VAMAS1
Application:
ELISA, WB, IHC-P, IF, ICC
Molecular Weight:
130 kDa(N terminal)/165 kDa(Full length)
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Uniprot:
Q9C000
Synonyms:
AIADK;CARD7;caspase recruitment domain protein 7;caspase recruitment domain-containing protein 7;CIDED;CLR17.1;death effector filament-forming Ced-4-like apoptosis protein;DEFCAP;DEFCAP-L/S;JRRP;MSPC;NAC;NACHT, leucine rich repeat and PYD (pyrin domain) containing 1;NACHT, leucine rich repeat and PYD containing 1;NACHT, LRR and PYD containing protein 1;NACHT, LRR and PYD domains-containing protein 1;NALP1;nucleotide-binding domain and caspase recruitment domain;nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1;PP1044;SLEV1;VAMAS1
Extra Details:
This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
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Blue Ice