A1620
DPYD Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A1620
- Additional Names:
- DHP|DHPDHASE|DPD|DPYD|DYPD
- Application:
- ELISA, WB
- Molecular Weight:
- 112kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDNPLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATETLILAFSLMNHL
- Uniprot:
- Q12882
- Synonyms:
- DHP;DHPDHASE;dihydropyrimidine dehydrogenase [NADP(+)];dihydrothymine dehydrogenase;dihydrouracil dehydrogenase;DPD
- Extra Details:
- The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice