A15962
PUS10 Rabbit polyclonal antibody

Size
£152.00
- SKU:
- A15962
- Additional Names:
- CCDC139|DOBI|Hup10|PUS10
- Application:
- ELISA, WB
- Molecular Weight:
- 60kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- VAGRYNKYSRNLPQTPWIIDGERKLESSVEELISDHLLAVFKAESFNFSSSGREDVDVRTLGNGRPFAIELVNPHRVHFTSQEIKELQQKINNSSNKIQVRDLQLVTREAIGHMKEGEEEKTKTYSALIWTNKAIQKKDIEFLNDIKDLKIDQKTPLRVLHRRPLAVRARVIHFMETQYVDEHHFRLHLKTQAGTYIKEFVHGDFGRTKPNIGSLMNVTADILELDVESVDVDWPPALDD
- Uniprot:
- Q3MIT2
- Synonyms:
- CCDC139;coiled-coil domain containing 139;coiled-coil domain-containing protein 139;DOBI;Hup10;pseudouridylate synthase 10;psi55 synthase;putative tRNA pseudouridine synthase Pus10;tRNA pseudouridine 55 synthase;tRNA pseudouridine synthase Pus10;tRNA pseudouridylate synthase;tRNA-uridine isomerase
- Extra Details:
- Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).
- Shipping Conditions:
- Blue Ice

