A15801
SF3B1 Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A15801
- Additional Names:
- Hsh155|MDS|PRP10|PRPF10|SAP155|SF3B1|SF3b155
- Application:
- ELISA, WB, IF, ICC
- Molecular Weight:
- 150kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAATELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYKKHRRTMIISPERLDPFADGFYSAA
- Uniprot:
- O75533
- Synonyms:
- Hsh155;MDS;pre-mRNA processing 10;pre-mRNA splicing factor SF3b, 155 kDa subunit;Pre-mRNA-splicing factor SF3b 155 kDa subunit;PRP10;PRPF10;SAP155;SF3b155;spliceosome-associated protein 155;splicing factor 3B subunit 1;splicing factor 3b, subunit 1, 155kDa
- Extra Details:
- This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Shipping Conditions:
- Blue Ice