DICER1 Rabbit polyclonal antibody

Size

£152.00

SKU:: A15799
Additional Names:: aviD|DCR1|Dicer|DICER1|Dicer1e|GLOW|HERNA|K12H4.8-LIKE|MNG1|RMSE2
Application:: ELISA, IF, ICC
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: KSIDSKSFISISNSSSAENDNYCKHSTIVPENAAHQGANRTSSLENHDQMSVNCRTLLSESPGKLHVEVSADLTAINGLSYNQNLANGSYDLANRDFCQGN
Uniprot:: Q9UPY3
Synonyms:: aviD;DCR1;Dicer;dicer 1, double-stranded RNA-specific endoribonuclease;dicer 1, ribonuclease type III;Dicer1, Dcr-1 homolog;Dicer1e;endoribonuclease Dicer;GLOW;helicase MOI;helicase with RNAse motif;HERNA;K12H4.8-LIKE;MNG1;RMSE2
Extra Details:: This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. This protein also acts as a strong antiviral agent with activity against RNA viruses, including the Zika and SARS-CoV-2 viruses. Alternative splicing results in multiple transcript variants.