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A15654

CD27 Rabbit polyclonal antibody

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£152.00

SKU:
A15654
Additional Names:
CD27|S152|S152. LPFS2|T14|TNFRSF7|Tp55
Application:
ELISA, WB
Molecular Weight:
50kda
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Mouse
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
ATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVRNCTITANAECACRNGWQCRDKECTECDPLPNPSLTARSSQALSPHPQPTHLPYVSEMLEARTAGHMQTLADFRQLPARTLSTHWPPQRSLCSSDFIR
Uniprot:
P26842
Synonyms:
CD27 antigen;CD27L receptor;S152;S152. LPFS2;T cell activation antigen S152;T-cell activation antigen CD27;T14;TNFRSF7;Tp55;Tumor necrosis factor receptor superfamily member 7;tumor necrosis factor receptor superfamily, member 7
Extra Details:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Shipping Conditions:
Blue Ice