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A15613

GLI3 Rabbit polyclonal antibody

Size

£152.00

SKU:
A15613
Additional Names:
ACLS|GCPS|GLI3|GLI3-190|GLI3FL|PAP-A|PAPA|PAPA1|PAPB|PHS|PPDIV
Application:
ELISA, WB, IHC-P, IF, ICC
Molecular Weight:
Refer to figures
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
This information is considered to be commercially sensitive.
Sequence:
NTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSNSGLELPLTDGGSIGDLSAIDETPIMDSTISTATTALALQARRNPAGTKWMEHVKLERLKQVNG
Uniprot:
P10071
Synonyms:
ACLS;GCPS;GLI-Kruppel family member GLI3;GLI3 form of 190 kDa;GLI3 full-length protein;GLI3-190;GLI3FL;glioma-associated oncogene family zinc finger 3;oncogene GLI3;PAP-A;PAPA;PAPA1;PAPB;PHS;PPDIV;transcriptional activator GLI3;zinc finger protein GLI3
Extra Details:
This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.
Shipping Conditions:
Blue Ice