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A15476

CDK5RAP2 Rabbit polyclonal antibody

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£152.00

SKU:
A15476
Additional Names:
C48|CDK5RAP2|Cep215|MCPH3
Application:
ELISA, WB
Molecular Weight:
250kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
GQRLLAEMDIQTQEAPSSTSQELGTKGPHPAPLSKFVSSVSTAKLTLEEAYRRLKLLWRVSLPEDGQCPLHCEQIGEMKAEVTKLHKKLFEQEKKLQNTMKLLQLSKRQEKVIFDQLVVTHKILRKARGNLELRPGGAHPGTCSPSRPGS
Uniprot:
Q96SN8
Synonyms:
C48;CDK5 activator-binding protein C48;CDK5 regulatory subunit-associated protein 2;centrosomal protein 215 kDa;Centrosome-associated protein 215;centrosomin;Cep215;MCPH3
Extra Details:
This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice