SMPD4 Rabbit polyclonal antibody

Size

£152.00

SKU:: A15473
Additional Names:: NEDMABA|NEDMEBA|NET13|NSMASE-3|NSMASE3|SKNY|SMPD4
Application:: ELISA, WB, IF, ICC
Molecular Weight:: 100kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: ITQAKHTAKSISDQCAESPAGHSFLSWLGFSSMDTNGSYTANDLDEMGQDSVRKTDEYLEKALEYLRQIFRLSEAQLRQFTLALGTTQDENGKKQLPDCIVGEDGLILTPLGRYQIINGLRRFEIEYQGDPELQPIRSYEIASLVRTLFRLSSAINHRFAGQMAALCSRDDFLGSFCRYHLTEPGLASRHLLSPVGRRQVA
Uniprot:: Q9NXE4
Synonyms:: NEDMABA;NEDMEBA;NET13;neutral sphingomyelinase 3;neutral sphingomyelinase III;NSMASE-3;NSMASE3;SKNY;sphingomyelin phosphodiesterase 4;sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
Extra Details:: The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network.