TFB1M Rabbit polyclonal antibody

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£152.00

SKU:: A15231
Additional Names:: CGI-75|CGI75|mtTFB|mtTFB1|TFB1M
Application:: ELISA, WB
Molecular Weight:: 40kda
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: QAAKQLSQNFLLDLRLTDKIVRKAGNLTNAYVYEVGPGPGGITRSILNADVAELLVVEKDTRFIPGLQMLSDAAPGKLRIVHGDVLTFKVEKAFSESLKRPWEDDPPNVHIIGNLPFSVSTPLIIKWLENISCRDGPFVYGRTQMTLTFQKEVAERLAANTGSKQRSRLSVMAQYLCNVRHIFTIPGQAFVPKPEVDVGVVHFTPLIQPKIEQPFKLVEKVVQNVFQFRRKYCHRGLRMLFPEAQRLESTGRLLELADIDPTLRPRQLSISHFKSLCDVYRKMCDEDPQLFAYNFREELKRRKSKNEEKEEDDAENYRL
Uniprot:: Q8WVM0
Synonyms:: CGI-75;CGI75;dimethyladenosine transferase 1, mitochondrial;h-mtTFB1;homolog of yeast mitochondrial transcription factor B;hTFB1M;mitochondrial 12S rRNA dimethylase 1;mitochondrial dimethyladenosine transferase 1;Mitochondrial transcription factor B1;mtTFB;mtTFB1;S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1
Extra Details:: The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness (AID).

Shipping Conditions:: Blue Ice