AARS Rabbit polyclonal antibody

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£152.00

SKU:: A15017
Additional Names:: AARS|CMT2N|DEE29|EIEE29|HDLS2|TTD8
Application:: ELISA, WB, IHC-P, IF, ICC
Molecular Weight:: 107 kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MDSTLTASEIRQRFIDFFKRNEHTYVHSSATIPLDDPTLLFANAGMNQFKPIFLNTIDPSHPMAKLSRAANTQKCIRAGGKHNDLDDVGKDVYHHTFFEM
Uniprot:: P49588
Synonyms:: AARS;alanine tRNA ligase 1, cytoplasmic;alanine--tRNA ligase, cytoplasmic;Alanyl-tRNA synthetase;alanyl-tRNA synthetase, cytoplasmic;alaRS;CMT2N;DEE29;EIEE29;renal carcinoma antigen NY-REN-42
Extra Details:: The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.