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A14989

HBG1 Rabbit polyclonal antibody

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£152.00

SKU:
A14989
Additional Names:
HBG-T2|HBG1|HBGA|HBGR|HSGGL1|PRO2979
Application:
ELISA, WB
Molecular Weight:
12kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVD
Uniprot:
P69891
Synonyms:
A-gamma globin;gamma A hemoglobin;gamma globin;gamma-1-globin;hb F Agamma;HBG-T2;HBGA;HBGR;hemoglobin gamma-1 chain;hemoglobin gamma-a chain;hemoglobin subunit gamma-1;hemoglobin, gamma A;hemoglobin, gamma, regulator of;HSGGL1;PRO2979
Extra Details:
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Shipping Conditions:
Blue Ice