ERLIN1 Rabbit polyclonal antibody

Size

£152.00

SKU:: A14843
Additional Names:: C10orf69|Erlin-1|ERLIN1|KE04|KEO4|SPFH1|SPG62
Application:: ELISA, WB, IHC-P, IP
Molecular Weight:: 39kda
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: KADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFGSNIPNMFVDSSCALKYSDIRTGRESSLPSKEALEPSGENVIQNKESTG
Uniprot:: O75477
Synonyms:: Band_7 23-211 Keo4 (Interim) similar to C.elegans protein C42C1.9;C10orf69;endoplasmic reticulum lipid raft-associated protein 1;erlin-1;KE04;KEO4;Protein KE04;SPFH domain family, member 1;SPFH domain-containing protein 1;SPFH1;SPG62;stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1
Extra Details:: The protein encoded by this gene is part of a protein complex that mediates degradation of inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum. The encoded protein also binds cholesterol and regulates the SREBP signaling pathway, which promotes cellular cholesterol homeostasis. Defects in this gene have been associated with spastic paraplegia 62.