USP15 Rabbit polyclonal antibody

Size

£152.00

SKU:: A1476
Additional Names:: UNPH-2|UNPH4|USP15
Application:: ELISA, WB, IF, ICC, IP
Molecular Weight:: 112 kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C 0.09% sodium azide. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: Q9Y4E8
Synonyms:: deubiquitinating enzyme 15;ubiquitin carboxyl-terminal hydrolase 15;ubiquitin thioesterase 15;ubiquitin thiolesterase 15;ubiquitin-specific-processing protease 15;UNPH-2;UNPH4
Extra Details:: This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2.