A14712
CBFA2T3 Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A14712
- Additional Names:
- CBFA2T3|ETO2|MTG16|MTGR2|RUNX1T3|ZMYND4
- Application:
- ELISA, WB
- Molecular Weight:
- 75kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- GQSLQGPTAVVADPVPGPPEAAHSLGPSLPVGAASPSEAGSAGPSRPGSPSPPGPLDTVPR
- Uniprot:
- O75081
- Synonyms:
- CBFA2/RUNX1 translocation partner 3;core-binding factor, runt domain, alpha subunit 2; translocated to, 3;ETO2;MTG16;MTG8-related gene 2;MTG8-related protein 2;MTGR2;myeloid translocation gene 8 and 16b;myeloid translocation gene on chromosome 16 protein;protein CBFA2T3;RUNX1T3;zinc finger MYND domain-containing protein 4;ZMYND4
- Extra Details:
- This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
- Shipping Conditions:
- Blue Ice