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A14344

MRI1 Rabbit polyclonal antibody

Size

£152.00

SKU:
A14344
Additional Names:
M1Pi|MRDI|MRI1|MTNA|Ypr118w
Application:
ELISA, WB
Molecular Weight:
45kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLAVELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEAVRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSRDGTLDGPQM
Uniprot:
Q9BV20
Synonyms:
M1Pi;mediator of RhoA-dependent invasion;methylthioribose-1-phosphate isomerase;methylthioribose-1-phosphate isomerase homolog;MRDI;MTNA;MTR-1-P isomerase;S-methyl-5-thioribose-1-phosphate isomerase;S-methyl-5-thioribose-1-phosphate isomerase 1;translation initiation factor eIF-2B subunit alpha/beta/delta-like protein;Ypr118w
Extra Details:
This enzyme functions in the methionine salvage pathway by catalyzing the interconversion of methylthioribose-1-phosphate and methythioribulose-1-phosphate. Elevated expression of the encoded protein is associated with metastatic melanoma and this protein promotes melanoma cell invasion independent of its enzymatic activity. Mutations in this gene may be associated with vanishing white matter disease (VMWD).
Shipping Conditions:
Blue Ice