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A14253

PTPRG Rabbit polyclonal antibody

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£152.00

SKU:
A14253
Additional Names:
HPTPG|PTPG|PTPRG|R-PTP-GAMMA|RPTPG
Application:
ELISA, WB
Molecular Weight:
140-162kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
YRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQRLHDRVVSKSAVRDSWNHDMTDFLENPLGTEASKVCSSPPIHMKVQPLNQTALQVSWSQPETIYHPPIMNYMISYSWTKNEDEKEKTFTKDSDKDLKATISHVSPDSLYLFRVQAVCRNDMRSDFSQTMLFQANTTRIFQ
Uniprot:
P23470
Synonyms:
H_RG317H01.1;HPTPG;protein tyrosine phosphatase gamma;protein tyrosine phosphatase, receptor type, gamma polypeptide;PTPG;R-PTP-GAMMA;receptor type protein tyrosine phosphatase gamma;receptor tyrosine phosphatase gamma;receptor-type protein phosphatase gamma;receptor-type tyrosine-protein phosphatase gamma;RPTPG
Extra Details:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.
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Blue Ice